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Minipig in Biomedical Research
Heart Disease

 01.Preventing phrenic nerve stimulation by a patch insulation in an intact swine heart model. (2014)

 02.Coarctation-induced degenerative abdominal aortic aneurysm in a porcine model (2013)

 03.Immediate Intramyocardial Bone Marrow-Derived Mononuclear Cells Implantation in Minipig Myocardium After Permanent Coronary Artery Ligation: Magnetic Resonance Imaging With Histopathologic and Immunochemical Correlation (2011)

 04.Intramyocardial Peptide Nanofiber Injection Improves Postinfarction Ventricular Remodeling and Efficacy of Bone Marrow Cell Therapy in Pigs (2010)

 05.Left Atrial Enlargement Induced By Pure Mitral Regurgitation: Time Frame In A New Swine Model (2010)

 06.Wave energy patterns of counterpulsation: a novel approach with wave intensity analysis. (2005)

Tissue Engineering

 01.An in vivo swine study for xeno-grafts of calcium sulfate-based bone grafts with human dental pulp stem cells (hDPSCs). (2015)

 02.Engineered autologous bone marrow mesenchymal stem cells: alternative to cleft alveolar bone graft surgery. (2012)

 03.Tissue engineering-based cartilage repair with mesenchymal stem cells in a porcine model. (2011)

 04.Bone Marrow Combined With Dental Bud Cells Promotes Tooth Regeneration in Miniature Pig Model (2010)

 05.Repair Of Large Cranial Defects By hBMP-2 Expressing Bone Marrow Stromal Cells: Comparison Between Alginate And Collagen Type I Systems (2010)

 06.Fibrin glue mixed with gelatin/hyaluronic acid/ chondroitin-6-sulfate tri-copolymer for articular cartilage tissue engineering: The results of real-time polymerase chain reaction (2007)

 07.Regeneration of dentin-pulp complex with cementum and periodontal ligament formation using dental bud cells in gelatin-chondroitin-hyaluronantri-copolymer scaffold in swine (2007)

 08.Repair of Porcine Articular Cartilage Defect with a Biphasic Osteochondral Composite (2007)

 09.Evaluation of articular cartilage repair using biodegradable nanofibrous scaffolds in a swine model: a pilot study (2007)

 10.The Emplantation of Non-Cell-Based Materials to Prevent The Recurrent Disc Herniation: An In Vivo Porcine Model Using Quantitative Discomanometry Examination (2007)

 11.Tissue engineering-based cartilage repair with allogenous chondrocytes and gelatin–chondroitin hyaluronan tri-copolymer scaffold: A porcine model assessed at 18, 24, and 36 week (2006)

 12.Repair of porcine articular cartilage defect with autologous chondrocyte transplantation (2005)

 13.Tooth Regeneration on Mini Pigs from Dental Stem Cells (2005)

Research Model Development

 01.Development of a dietary induced metabolic syndrome model using miniature pigs-invovlement of ampk and sirt1. (2014)

 02.Injection of autologous bone marrow cells in hyaluronan hydrogel improves cardiac performance after infarction in pigs. (2014)

 03.Intraoperative neuromonitoring for the early detection and prevention of RLN traction injury in thyroid surgery: a porcine model. (2014)

 04.Successfully seal pancreatic end after thermal distal pancreatectomy using needle arrays in alternating electromagnetic fields. (2013)

 05.Partial nephrectomy without renal ischemia using an electromagnetic thermal surgery system in a porcine model(2013)

 06.Partial splenectomy using an electromagnetic thermal surgery system in a porcine model. (2013)

 07.Rejuvenation of aged pig facial skin by transplanting allogeneic granulocyte colony-stimulating factor-induced peripheral blood stem cells from a young pig. (2013)

 08.Percutaneous transgastric traction-assisted esophageal endoscopic submucosal dissection: a randomized controlled trial in a porcine model. (2012)

 09.Simulating target lesion for endoscopic submucosal dissection training in a live pig model. (2012)

 10.A novel injectable chitosan/polyglutamate polyelectrolyte complex hydrogel with hydroxyapatite for soft-tissue augmentation(2012)

 11.Lateral position with the remaining lung uppermost improves matching of pulmonary ventilation and perfusion in pneumonectomized pigs. (2011)

 12.Eyes in the needle: novel epidural needle with embedded high-frequency ultrasound transducer--epidural access in porcine model. (2011)

 13.Early Erythropoietin Therapy Attenuates Remodeling and Preserves Function of Left Ventricle in Porcine Myocardial Infarction. (2011)

 14.Bloodless liver resection using needle arrays under alternating electromagnetic fields. (2010)

 15.Effects of thermal preconditioning on the ischemiareperfusionnyinduced acute lung injury in minipigs (2007)



 01.Transplantation of embryonic stem cells improves the regeneration of periodontal furcation defects in a porcine model. (2013)

 02.A translational approach in using cell sheet fragments of autologous bone marrow-derived mesenchymal stem cells for cellular cardiomyoplasty in a porcine model. (2013)

 03.Immunomodulatory effects of bone marrow-derived mesenchymal stem cells in a swine hemi-facial allotransplantation model. (2012)

 04.Autologous mesenchymal stem cells prevent transplant arteriosclerosis by enhancing local expression of interleukin-10, interferon-γ, and indoleamine 2,3-dioxygenase. (2012)

 05.Autologous bone marrow cell implantation attenuates left ventricular remodeling and improves heart function in porcine myocardial infarction: An echocardiographic, six-month angiographic, and molecular–cellular study (2011)

 06.Prolongation of composite tissue allotransplant survival by treatment with bone marrow mesenchymal stem cells is correlated with T-cell regulation in a swine hind-limb model (2011)

 07.Intramedullary Cavity as Implantation Site for Bioartifical Pancreas: Preliminary In Vivo Study (2010)

 08.Mesenchymal Stem Cells Prolong Composite Tissue Allotransplant Survival in a Swine Model (2009)

 09.Six-month Angiographic Study of Immediate Autologous Bone Marrow Mononuclear Cell Implantation on Acute Anterior Wall Myocardial Infarction Using a Mini-Pig Model (2009)

 10.Large-Scale Bicortical Skull Bone Regeneration Using Ex Vivo Replication-Defective Adenoviral-Mediated Bone Morphogenetic Protein-2 Gene-Transferred Bone Marrow Stromal Cells And Composite Biomaterials (2009)

 11.Swine Hemi-Facial Composite Tissue Allotransplantation: A Model to Study Immune Rejection1 (2008)

 12.Porcine Heterotopic Composite Tissue Allograft Transplantation using A Large Animal Model for Preclinical Studies (2006)

Pharmacological Research

 01.Effect of tacrolimus on myocardial infarction is associated with inflammation, ROS, MAP kinase and Akt pathways in mini-pigs (2013)

 02.Innate immune response after acute myocardial infarction and pharmacomodulatory action of tacrolimus in reducing infarct size and preserving myocardial integrity (2013)

 03.Prostaglandin E2 Potentiates Mesenchymal Stem Cell–Induced IL-10+IFN-g+CD4+ Regulatory T Cells To Control Transplant Arteriosclerosis (2013)

 04.Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction(2012)

 05.Metabolism of Dicentrine: Identification of the Phase I and Phase II Metabolites in Miniature Pig Urine (2010)

Basic Research

 01.Determination of hematological parameters in miniature pigs (2018)

 02.Empirical Selection of Informative Microsatellite Markers within Co-ancestry Pig Populations Is Required for Improving the Individual Assignment Efficiency (2014)

 03.The phylogenetic status of typical Chinese native pigs: analyzed by Asian and European pig mitochondrial genome sequences. (2013)

 04.Mitochondrial genome of Taiwan pig (Sus Scrofa) (2011)

 05.Interpopulation and intrapopulation maternal lineage genetics of the Lanyu pig (2011)

 06.Selection and utilization of indigenous mini-pig (2011)

 07.Serum Testosteron and Progesteron Concentrations in Lanyu Pigs (2010)

 08.Microsatellite Maker Combination and Method For Identifying Lanyu Pig Breed (2010)

 09.Minipigs in Biomedical Research (2010)

 10.Genetic Variation and Phylogenetics of Lanyu and Exotic Pig Breeds in Taiwan Analyzed By Nineteen Microsatellite Markers (2008)

 11.Low Levels of Haptoglobin and Putative Amino Acid Sequence in Taiwanese Lanyu Miniature Pigs (2007)

 12.The Type I Lanyu Pig Has A Maternal Genetic Lineage Distinct from Asian and European Pigs (2007)

 13.Influence of Age on The Electrocardiographic Waves in Taiwanese Lan-Yu Miniature Pigs (1999)

Review of Pig Models

 01.醫療科技創新的新利器-白色賓朗豬 (2011)

 02.以蘭嶼迷你豬評估不同植體螺紋設計和間距對骨整合之影響 (2011)

 03.小型豬於生物醫學之應用 (2010)

Taitung Animal Propagation Station,
Livestock Research Institute, Council of Agriculture, Executive Yuan
No.30, binlang Vil., Beinan Township, Taitung County 954, Taiwan (R.O.C.) TEL:089-224634 FAX:089-229211